From Judith Rosen on facebook:
This is fascinating.
I mean, we all sort of “know” that our individual body cells have sensory capacities of their own and even the ability to form “memory” and to “learn”– differently from how our minds do it, but exactly the same in that it’s all about innate model-based guidance and additional model building from experience, right? It’s not something we generally think about (unless you’re as nerdy and deeply curious as I am and, if so, I think I love you!)… But these are indisputable truths about our own bodies– we can prove it is so. What does a vaccine do but build a new memory model in our immune system?
But even so, knowing that, it is freaky to watch cells figuring out a maze… going the wrong way, then turning around and going backward to that last turn… and taking the correct path to get through and exit the maze. The very fact that exiting is a goal is interesting! But the communication happening as successful paths are “marked” just blows my mind. This is Anticipation at work and it’s a really cool bit of scientific work.
Paper also available at: https://sci-hub.tw/10.1126/science.aay9792