A view or perspective on the world
6th International Conference for Systems and Complexity Sciences for Health
6th International Conference for Systems and Complexity Sciences for Health – ISSCSH
Jarrod Shilts, Yannik Severin, Francis Galaway, Nicole Müller-Sienerth, Zheng-Shan Chong, Sophie Pritchard, Sarah Teichmann, Roser Vento-Tormo, Berend Snijder & Gavin J. Wright
Nature volume608,pages397–404 (2022)
The human immune system is composed of a distributed network of cells circulating throughout the body, which must dynamically form physical associations and communicate using interactions between their cell-surface proteomes1. Despite their therapeutic potential2, our map of these surface interactions remains incomplete3,4. Here, using a high-throughput surface receptor screening method, we systematically mapped the direct protein interactions across a recombinant library that encompasses most of the surface proteins that are detectable on human leukocytes. We independently validated and determined the biophysical parameters of each novel interaction, resulting in a high-confidence and quantitative view of the receptor wiring that connects human immune cells. By integrating our interactome with expression data, we identified trends in the dynamics of immune interactions and constructed a reductionist mathematical model that…
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Nov 16President’s Series 22: Concepts of Organisation and Discovering CyberneticsAngus Jenkinson explores fundamental concepts of organisation leading in to a wider discussion of our varying experiences of cybernetics
President’s Series 22: Concepts of Organisation and Discovering Cybernetics Tickets, Wed 16 Nov 2022 at 17:00 | Eventbrite
Agnes Callard on AspirationSep 28 2020
Agnes Callard on Aspiration – Econlib
Excellent.
NOVEMBER 11TH, 2022 | 51:05 | E95
John Krakauer Part 1: Taking Multiple Perspectives on The Brain | COMPLEXITY
Systems Lessons of the Global Problematique: Valuing Connection
Today, greenhouse gas emissions are rising again while questions about how to spur economic growth continue. I wonder, are we missing the connection? Might a move away from reduction help us to understand our shared options?
Systems Lessons of the Global Problematique: Valuing Connection · Journal of Design and Science
via @daviding
World Hypotheses
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World Hypotheses: A Study in Evidence, by Stephen C. Pepper (1942), presents four relatively adequate world hypotheses (or world views or conceptual systems) in terms of their root metaphors: formism (similarity), mechanism (machine), contextualism (historical act), and organicism (living system).
In World Hypotheses, Pepper demonstrates the error of logical positivism, that there is no such thing as data free from interpretation, and that root metaphors are necessary in epistemology. In other words, objectivity is a myth because there is no such thing as pure, objective fact. Consequently, an analysis is necessary to understand how to interpret these ‘facts.’ Pepper does so by developing the “[root metaphor method, …] and outlines what he considers to be four basically adequate world hypotheses (world views or conceptual systems): formism, mechanism, contextualism, and organicism.” He identifies the strengths and weaknesses of each of the world hypotheses as well as the paradoxical and sometimes mystifying effects of the effort to synthesize them.[1]
World Hypotheses – Wikipedia
Just found Defence Research and Development Canada | Recherche et développement pour la défense Canada‘s 2007 paper:
Post | LinkedIn
Complexity and Chaos – State-of-the-Art; Formulations and Measures of Complexity, https://lnkd.in/ggi3dYXt
Listing 64 different technical formulations of complexity and chaos.
What technical definitions do you think are missing?
#complexity #chaos
RELEASE | HEALTH BEYOND MEDICINE. A PLANETARY THEORY EXTENSIONPosted on Oct 24, 2022 by Dr. Steffen Roth
Release | Health beyond medicine. A planetary theory extension | Dr. Steffen Roth
Nov 20In search of an erotic framework for CyberneticsInspired on the circularity of desire, an erotic approach may bring new insights on concepts such as the observer, control and black box.ByAmerican Society for CyberneticsFollow213 followersWhen and whereDate and timeSun, November 20, 2022, 12:00 PM – 1:30 PM EST
In search of an erotic framework for Cybernetics Tickets, Sun, Nov 20, 2022 at 12:00 PM | Eventbrite
Place-based change community of practiceUsing ‘place’ helps practitioners reach beyond traditional systems to invite multiple perspectives and unite people around shared ambitions.
Place-based change community of practice – Renaisi
Beyond Systems ThinkingTo deal with the current global polycrisis, we need cultural and mental transformation. This MOOC is the second of four MOOCs that hybridize science, design and transformative praxis. This joint learning journey is a fluid, intervention-driven, synergistic process addressing complex challenges with regional focus. It entails a critical look at systems thinking, tools to view complexity from above, basics of social network analysis, resilience assessment, circularities, and systemic innovation.
Beyond Systems Thinking | edX
Systems as a concept and the concepts of system science
ISSS 10 Sept 2022 Gary Smith
Systems as a concept and the concepts of system science on Vimeo
Some thoughts on systems coaching
Alice Evans
Jun 28
When I entered the world of funding and systems and complexity in 2013 by joining a charitable foundation in the newly created role of Director of Systems Change, the experience was daunting and overwhelming. The job title was confusing, expectations were high, and no one – let alone the new director – knew where to begin. But the experience was also delightfully humbling and enabled me to learn from and become inspired by a wonderful array of systems thinkers, coaches, and other wonderful folk.
Some thoughts on systems coaching – by Alice Evans
Integrative Design for Systems ChangeWHAT IS THIS?OverviewIf you’re thinking about using design in the social sector, this collection will help you get started with learning about core methodologies, stories from practitioners’ in the field, and a couple activities that you can apply towards your own work. If you’re curious to learn even more in depth, check out the d.school’s Designing for Social Systems program page.
Integrative Design for Systems Change — Stanford d.school
Systems Community of Inquiry 
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